Altered Functional Connectivity of Cerebello-Cortical Circuit in Multiple System Atrophy (Cerebellar-Type)
نویسندگان
چکیده
منابع مشابه
Altered Functional and Causal Connectivity of Cerebello-Cortical Circuits between Multiple System Atrophy (Parkinsonian Type) and Parkinson’s Disease
Lesions of the cerebellum lead to motor and non-motor deficits by influencing cerebral cortex activity via cerebello-cortical circuits. It remains unknown whether the cerebello-cortical "disconnection" underlies motor and non-motor impairments both in the parkinsonian variant of multiple system atrophy (MSA-P) and Parkinson's disease (PD). In this study, we investigated both the functional and ...
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In the current study, FOur-dimensional Consistency of local neural Activities (FOCA) analysis was used to investigate the local consistency by integrating the temporal and spatial information of the local region. In the current study, resting-state fMRI data of 69 schizophrenia patients and 70 healthy controls were collected. FOCA was utilized to investigate the local consistency. Moreover, Gra...
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Backgrounds and Purpose: Multiple system atrophy (MSA) is mainly a sporadic progressive neurodegenerative disease of unknown etiology. Typical histological findings of MSA are observed in the striatum, substantianigra, olivopontocerebellar pathways, the intermediolateral cell columns of the spinal cord, and the cerebellum. Similar findings have also been described in motor and supplementary mot...
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BACKGROUND AND PURPOSE We investigated the cognitive profiles in a large sample of patients with multiple system atrophy-cerebellar ataxia (MSA-C) and compared directly them in patients with clinical diagnosis of probable MSA-C without dementia and control subjects with intact cognition. METHODS We prospectively enrolled 26 patients with clinical diagnosis of probable MSA-C. All patients unde...
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Although volumetric and activation changes in the cerebellum have frequently been reported in studies on major depression, its role in the neural mechanism of depression remains unclear. To understand how the cerebellum may relate to affective and cognitive dysfunction in depression, we investigated the resting-state functional connectivity between cerebellar regions and the cerebral cortex in ...
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ژورنال
عنوان ژورنال: Frontiers in Neuroscience
سال: 2019
ISSN: 1662-453X
DOI: 10.3389/fnins.2018.00996